PDO (Polydioxanone) threads are synthetic absorbable suture material used in cardiac and pediatric surgeries for over 50 years. The threads, when placed in areas of skin laxity I a matrix like pattern, provide a subtle instant lift followed by collagen induction via a "selective inflammatory response". This leads to collagen and new blood vessels being laid down around the thread matrix for approximately 12 weeks, rejuvenating and tightening the area.